A fib and arterial throbmosis

Describe the cardiac arrhythmia and antomic features that lead to formation of thrombi in the left atrial appendage
describe the consequences of thrombi from untreated Atrial fibrillation and its treatment
describe the readons of thrombus formation in arteries
Identify the main drugs that are used to treat arterial thromnbosis and describe their mode of action

Atrial fibrillation

DOACs redice the risk of stroke be about 70% Warfarin by 64% Aspirin by only about 22%

atherosclerotic plaque rupture leads to high coagulation

Platelets are key players in arterieal thombosis

Common risk factors for arterial thrombosis

ATHEROSCLEROSIS

hyperlipidaemis hypertension diabetes cigarette smoking male family history polycythaemia

raised coagualtion

Infarction can lead to Afib

apirin second antiplatelet - clopidogrel anticoagulant fibrinolytic must be used within a few days heparin

heparin induced thrombocytopenia progressing antibody binds to heparin and platelet factor 4 an platelets

type I and type II