Introduction to Inheritance and Risk Assessment Tut
Annika talks about what would happen in a mutation affects gene dosage
sometimes mutations can lead to reduced function but still functional
talks about: Penetrance penetrance is how many people will display disease phenotype when possessing disease phenotype.
Expressivity expressivity is how much the phenotype comes through. eg mild and severe disease
she talks about pedigrees and basic genetics
Dynamic mutations like CAG repeat with huntingtons. gets worse with each generation