Physiology 2 Excitable Membranes

Objectives:

  1. Understand what drives the membrane potential and how to predict it
  2. understand the role os passive potentials
  3. understand the role of action potentials in the nervous system and the mechanisms of their generation
Objective based questioning:

Content:

Understand what drives the membrane potential and how to predict it ✅

The nernst equation can give us the membrane difference for a single ion and how to predict changes. the ratio of ion concentrations outside the cell compared to inside.

Value of an equilibrium potential

Calculation of the RMP

If you combine a few Nernst equations together combined with permeability you can calculate the ideal equilibrium potential for a cell.

Understand the role of passive (aka local or graded) potentials

the whole spiel is that localised changes in the cell body is how information get into a neuron and these graded potentials can sum to make an action potential

Understand the role of action potentials in the nervous system and the mechanisms of their generation

action potentials are the self sustaining wave of changing charge that occurs upon membrane potential rising above threshold

knowledge is already in your brain

Summary