Altered metabolism - DM, Gout, Trauma Regulation of metabolism Diabetes mellitus
Topics we covered in this lecture
- High and low blood sugar
- What diabetes is. What the categories are. How they are diagnosed.
- Acute and chronic complications of diabetes
- Treatment of diabetes
- Biochemistry behind the development of the acute and chronic complications
- Biochemistry behind the molecular basis of insulin resistance
Some learning questions/aims
- Discuss causes of hypoglycaemia.
- What are the differences between Type 1 and Type 2 diabetes?
- What are the acute and chronic complications of Type 1 and Type 2 diabetes?
- What are the biochemical mechanisms behind the development of these complications?
- What are the consequences of protein glycation?
- Discuss possible sites and mechanisms of insulin resistance.
- What are the steps in the progression towards Type 2 diabetes?
- Be familiar with molecules that are targeted by diabetes therapies.