Objectives for module
- Understand renal anatomy, physiology and pathophysiology
- Link changes in kidney physiology to clinical presentations
- Particularly important in acute kidney injury
- Drugs work by correcting pathophysiology ACEI, ARBs, diuretics, SGLT2 inhibitors
- Kidneys are the key regulator of blood pressure and hypertension.
- Understand the importance of urinalysis – haematuria and proteinuria, to detect kidney disease.
- Importance of proteinuria for the prognosis of kidney and cardiovascular disease.
- Glomerulonephritis – understand the basic immunopathology that explains the different clinical presentations
- Chronic kidney disease – diabetic kidney disease as the main example. Know the importance of factors which contribute to the progression of kidney disease.
- CKD is the biggest risk for CVD
- Extra-renal manifestations of CKD
- Integration with other modules cardiovascular, metabolic – diabetes, pharmacology.
- Overview provided in lectures to link with2 integrated clinical cases to explore aspects of kidney disease
- acute glomerulonephritis
- Diabetic kidney disease – progressive chronic kidney disease