This is a MonoOxidaseAmineInhibitor. This stops the breakdown of dopamine in the cleft, increaseing the signalling provided by each release. It can offer some antidepressant effects, and increases levels of noradrenaline too.

This can be used with L-DOPA, and can be given with early stages of the disease

Side effects of selegiline

  • twitching twisting and uncontrolled reptitive movements
  • Insomnia
  • Loss of appetite
  • Severe interactions with reuptake inhibitors